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The Anion Gap:The equivalents of cations in a solution always balances the equivalents of anions. However, by tradition, not every ionic constituent is reported by the lab. (Do you really want to know that much detail in any case?!). The simplest reports may only give the [Na+], [Cl-], and the [HCO3-]. The "real" balance is given by the equation: [Na] + [other cations] = [Cl] + [HCO3] + [other anions] rearranging: [Na] - ([Cl] + [HCO3]) = [other anions] - [other cations] = "Anion Gap" Normal values for the Anion Gap are 8-16 mEq/L plasma The Anion Gap is a useful shorthand measure, particularly in the differential diagnosis of acid/base disorders. |
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Copyright 1999, Joe Patlak, Department of Physiology, University
of Vermont. |
